: an acute inflammatory disease that is caused by spirochetes (genus Borrelia, especially B. burgdorferi) transmitted by ticks (genus Ixodes and especially I. scapularis), that is usually characterized initially by a spreading red annular erythematous skin lesion and by fatigue, fever, and chills, and that if left untreated may later manifest itself in joint pain, arthritis, and cardiac and neurological disorders
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Merriam-Webster unabridged
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